Matrix metalloproteinases: a role in emphysema?
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چکیده
منابع مشابه
Matrix metalloproteinases: a role in emphysema?
The combined observations that (1) an inherited deficiency activity was found to be most strongly related to smoking, confirming previous studies. Interestingly, there was no of the major serum neutrophil elastase inhibitor, a1-proquantitative relationship between the enzyme levels, loss teinase inhibitor (a1-PI; a1-antitrypsin) predisposes to deof lung function, or degree of emphysema. Since t...
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Mammalian palatogenesis depends on palatal shelf elevation, medial edge epithelium (MEE) breakdown, and mesenchyme flow. These all require matrix remodeling, which is controlled in part by the family of matrix metalloproteinases (MMPs). We used an organ culture system to examine the effect of a general MMP inhibitor (BB3103) on mouse palatogenesis. Palates cultured in 20 micro M BB3103 containe...
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Matrix metalloproteinases (MMPs) are a family of neutral proteinases that are important in normal development, cellular differentiation or migration, angiogenesis, neurogenesis, wound repair, and a wide range of pathological processes such as oxidative stress and neuroinflammation. MMPs have been demonstrated to increase the permeability of the blood–brain barrier (BBB) by degrading the c...
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ژورنال
عنوان ژورنال: Thorax
سال: 1997
ISSN: 0040-6376
DOI: 10.1136/thx.52.6.495